Researchers determine architecture of a macromolecular complex regulating gene expression and DNA repair

Researchers at the Institute for Systems Biology, in collaboration with the University of California, San Francisco, the University of Colorado Boulder, and the Fred Hutchinson Cancer Research Center, have mapped the architecture of the multi-subunit TFIIH complex.

Researchers determine architecture of a macromolecular complex regulating gene expression and DNA repair
Researchers determine architecture of a macromolecular complex regulating gene expression and DNA repair

Researchers Find Key Protein Tied to Production of ‘Good’ Cholesterol

Researchers at the Institute for Systems Biology, in collaboration with Seattle Biomedical Research Institute and Oregon State University, have identified a key regulator of the macrophage response to inflammation that prevents the efflux of cholesterol to HDL.

Researchers Find Key Protein Tied to Production of ‘Good’ Cholesterol
Researchers Find Key Protein Tied to Production of ‘Good’ Cholesterol
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