Promotion: Dr. Jie Luo Becomes Senior Research Scientist

Congratulations to Dr. Jie Luo, of the Ranish Lab, who has been promoted to senior research scientist. From Dr. Jeff Ranish: "Jie Luo is an extremely dedicated and talented scientist. When he joined ISB in 2006 as a postdoctoral fellow, he had no experience in mass spectrometry-based proteomics. Now he is a leader in the field of structural and functional proteomics."

Promotion: Dr. Jie Luo Becomes Senior Research Scientist
Promotion: Dr. Jie Luo Becomes Senior Research Scientist

Researchers determine architecture of a macromolecular complex regulating gene expression and DNA repair

Researchers at the Institute for Systems Biology, in collaboration with the University of California, San Francisco, the University of Colorado Boulder, and the Fred Hutchinson Cancer Research Center, have mapped the architecture of the multi-subunit TFIIH complex.

Researchers determine architecture of a macromolecular complex regulating gene expression and DNA repair
Researchers determine architecture of a macromolecular complex regulating gene expression and DNA repair

Researchers Find Key Protein Tied to Production of ‘Good’ Cholesterol

Researchers at the Institute for Systems Biology, in collaboration with Seattle Biomedical Research Institute and Oregon State University, have identified a key regulator of the macrophage response to inflammation that prevents the efflux of cholesterol to HDL.

Researchers Find Key Protein Tied to Production of ‘Good’ Cholesterol
Researchers Find Key Protein Tied to Production of ‘Good’ Cholesterol

Cancer Treatment: A Systems Approach

Cancer cells, for decades regarded as a uniform mass of identical (“clonal”) cells, are not like the soldiers of a traditional army, trained to act and respond in unison. Cancer cells, even within a genetic clone, express enormous individuality akin to guerrilla fighters, each with unique strengths, weaknesses and distinct behaviors.

Cancer Treatment: A Systems Approach
Cancer Treatment: A Systems Approach
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